• In MM the optimal sequence or combination of the different

  2019-05-13

  

  In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first

• Through analyses of data from surveys

  2019-05-10

  

  Through analyses of data from surveys that used similar measures, methods, and ethical standards across 44 countries, Heise and Kotsadam have taken an important step towards an improved understanding of intimate partner violence and informing interventions. However, much work remains to be done. In

• Algunos cambios sin embargo estaban llegando para tener

  2019-05-10

  

  Algunos cambios, sin embargo, estaban llegando para tener gran influencia. En la Europa nórdica ciertos oscuros eruditos habían empezado EHop-016 crear las bases de una ciencia fundamental para la burguesía moderna, la filología clásica, y sobre ella un neohumanismo fundamentado en la resurrección d

• br INTRODUCCI N La historia pol tica de Colombia

  2019-05-10

  

  INTRODUCCIÓN La historia política de Colombia se ha desarrollado en una tensión permanente. Como lo plantea Cárdenas, esta tensión siempre ha surgido entre la guerra y la búsqueda de la paz. Según el autor: “desde el mismo origen del Estado colombiano, la violencia y los conflictos han sido un el

• Sin embargo la mayor a de los aventureros se

  2019-05-10

  

  Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob

• br Case report A year old man with dilated cardiomyopathy

  2019-05-10

  

  Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200

• Introduction Researchers have long followed

  2019-05-10

  

  Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pa

• estrone It is possible that this contradiction may be due to

  2019-05-09

  

  It is possible that this contradiction may be due to referral bias in the studies of Brugada et al. [20,21]. Second, it is possible that time of day influences the results of PES. The magnitude of ST-segment elevation in the right precordial leads in BS varies spontaneously over days and during the

• For example glutamate is increasingly recognized as one

  2019-05-09

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal auda function, glutamate is also intimately involved

• bosentan Pilsicainide might increase hERG proteins via facil

  2019-05-09

  

  Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica

• Limitations of meta analyses are often based on the strength

  2019-05-09

  

  Limitations of meta-analyses are often based on the strength of the data available. Only 26% of the eligible studies were judged to be at low risk of overall bias in this analysis. Other studies may have been at low risk for bias but failed to report information necessary for this determination. All

• Second although it is an important and

  2019-05-09

  

  Second, although it is an important and biologically plausible refinement, risk-factor adjustment based on lack of access to improved water in rural areas and urban slums could be open to criticism, as the authors acknowledge. The imperfect relation between access to improved water and consumption o

• When the analysis was matching with propensity score OS was

  2019-05-09

  

  When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic

• br In a reanalysis of our results Michelle Remme and

  2019-05-09

  

  In a reanalysis of our results, Michelle Remme and colleagues (October, 2015) found that “secondary schooling might [even] be as good an HIV investment as male circumcision”, not to mention more expensive biomedical options. As Remme and colleagues rightly point out, we had excluded from our cost-

• br Methods This was a

  2019-05-09

  

  Methods This was a retrospective review of hospital records of dental patients who were treated under GA from January 2006 until November 2015. All participants who attended our hospital were first examined to evaluate their behavioral capabilities and their psychological and physical disabilitie

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