• br Introduction Adenosine deaminase ADA also known

  2024-08-14

  

  Introduction Adenosine deaminase (ADA), also known as adenosine aminohydrolase, is a key enzyme involved in the purine metabolism that converts adenosine to inosine irreversibly (Lupidi et al., 1997). It is a zinc containing metalloenzyme present in both prokaryotes and eukaryotes. In humans ADA

• The first suggestions that the cleaved intracellular domain

  2024-08-14

  

  The first suggestions that the cleaved intracellular domain of APP, AICD, might transit to the nucleus and hence selectively regulate gene transcription arose from analogies with the Notch receptor signalling system where similar intra-membrane proteolysis occurs [84], [85] and it was later confirme

• Introduction hydroxytryptamine HT is found throughout the bo

  2024-08-14

  

  Introduction 5-hydroxytryptamine (5-HT) is found throughout the body and influences smooth muscle activity in various tissues including the intestine, vasculature and urinary HOAt (Kim and Camilleri, 2000, Klarskov and Horby-Petersen, 1986, Mohammad-Zadeh et al., 2008). The current classification

• protase Phagosomes acquire some hydrolases early during

  2024-08-14

  

  Phagosomes acquire some hydrolases early during their journey from the cell surface to lysosomes. An example for such hydrolase is cathepsin H which is most concentrated in the early phagosome at a pH of approximately 6.3 (Claus et al., 1998), the pH optimum of enzyme activity (Schwartz and Barrett,

• br Methods and materials br

  2024-08-14

  

  Methods and materials Results Discussion GPCR regulation in response to agonist stimulation is common to nearly all GPCRs and is essential in physiological systems to limit persistent signalling. In this study we have investigated the [Pyr1]apelin-13-induced trafficking and desensitization

• Prostate cell growth and prostate carcinogenesis are not onl

  2024-08-14

  

  Prostate cell growth and prostate carcinogenesis are not only mediated by androgens, they are also dependent on functional insulin receptor (IR) and insulin-like growth factor-1 (IGF-1) receptor (IGF1R) signaling. Previous studies addressed this issue and reported a correlation between high insulin

• and LO are members of the lipoxygenase

  2024-08-13

  

  5- and 12/15-LO are members of the lipoxygenase family that convert arachidonic 81 9 into lipid mediators such as leukotriene B4 (LTB) and 12()-hydroxyeicosatetraenoic acid (HETE) and 15()-HETE, respectively. Evidence from several in vitro and in vivo studies has shown that activation of the 5- and

• Data used in preparation of this article

  2024-08-13

  

  Data used in preparation of this article were obtained from the ADNI database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing o

• br Preliminary remarks Expression of the transcription facto

  2024-08-13

  

  Preliminary remarks Expression of the transcription factor aryl hydrocarbon receptor (AHR) and the AHR-repressor (AHRR) are both strikingly high in the IKK-16 hydrochloride mg of barrier organs skin and gut [1,2]. It is generally assumed that this reflects their role in linking environmental fact

• br Impact of global AHR

  2024-08-13

  

  Impact of global AHR deficiency on diet-induced obesity Two subsequent studies in which AHR function was affected at the whole animal level corroborated the role of AHR in dietary obesity. Xu et al. [14] showed that on a high-fat diet, both AHR-deficient Ahr−/− and hemizygous Ahr+/− mice gained s

• ADA catalyzes the deamination of adenosine and deoxyadenosin

  2024-08-13

  

  ADA catalyzes the deamination of adenosine and deoxyadenosine into their respective inosine nucleoside (Cristalli et al., 2001). This conversion is an initial step in a series of reactions responsible for lymphocyte proliferation and differentiation. Moreover, ADA is considered an indicator of cellu

• The AChR is composed of five

  2024-08-13

  

  The AChR is composed of five homologous, membrane-spanning subunits. AChRs containing two α, one β, one δ and one γ subunit (AChRγ) predominate during embryonic development and mice lacking AChRγ die at birth (Takahashi et al., 2002). After birth, the AChRγs are replaced during the first 2 postnatal

• Because serum ATX activity and plasma LPA are well correlate

  2024-08-13

  

  Because serum ATX activity and MAPK Inhibitor Library LPA are well correlated with liver fibrosis stage histologically, both of these parameters merit consideration as novel markers of fibrosis. However, serum ATX activity may be a more useful test from a clinical laboratory perspective. First, LPA

• Furthermore different s http www apexbt

  2024-08-12

  

  Furthermore, different studies have described the APP as useful biomarkers in monitoring the post-ovariohysterectomy period in bitches with pyometra [12,14,52,53], similar to what was observed in queens in the present study. In our study, significant decreases in concentrations of a major (SAA) and

• Recently dairy proteins obtained from whey

  2024-08-12

  

  Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional val

15887 records 100/1060 page Previous Next First page 上5页 96979899100 下5页 Last page