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The OptiVol Fluid Index OVFI which is
2019-06-27

The OptiVol Fluid Index (OVFI), which is derived from changes in intrathoracic impedance, can effectively assess HF by analyzing the changes in the intrathoracic impedance detected by the original OptiVol algorithm. Small et al. previously determined that a frequent and extended threshold crossing p
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Two other groups subsequently published further data on
2019-06-27

Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant
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br The follow up clinic
2019-06-27

The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ
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In our study the levels of BALP PINP
2019-06-27

In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (pbone raas inhibitor markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to predict the risk of SR
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In addition to inducing IKs dysfunction through dominant neg
2019-06-27

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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The study by Quentin Vincent and colleagues
2019-06-27

The study by Quentin Vincent and colleagues in makes good use of data collected with the WHO Buruli ulcer forms. Vincent and colleagues exploited and analysed data for 1357 laboratory-confirmed cases of Buruli ulcer during 10 years at the treatment centre in Pobè, Benin, to provide qualitative and q
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En esta columna al mismo tiempo que se congratulaban
2019-06-26

En esta columna, al mismo tiempo que se congratulaban de informar la generosa donación de Andrew Carnegie, de 250 mil dólares para una biblioteca en La Habana, señalaban la inexorable presencia del poder foráneo estadounidense. Una vez inaugurada la República, afirmaba La Lucha: “Después del 20 de m
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br Planteamientos Previos El presente estudio
2019-06-26

Planteamientos Previos El presente estudio muestra la estrecha relación entre los procesos identitarios y las transformaciones de los contextos migratorios. Centrándose en el caso de los migrantes indígenas de Otavalo (Ecuador) en una de las ciudades del sur de España, la investigación parte de u
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Despite taking hydroxyurea for months his leukocytosis
2019-06-26

Despite taking hydroxyurea for 6 months, his leukocytosis, splenomegaly, and constitutional symptoms were poorly controlled and his performance status and overall function had declined even further. There was little clinical benefit to gain by increasing the hydroxyurea dose further especially in th
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nmda receptor Despite impressive progress towards eliminatio
2019-06-26

Despite impressive progress towards elimination, social unrest, gaps in the coverage of populations at risk, competing health interests, and possible donor fatigue present challenges to successful elimination of human African trypanosomiasis caused by and subsequent maintenance of this status. The t
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br Heart rate turbulence HRT HRT was introduced
2019-06-26

Heart rate turbulence (HRT) HRT was introduced by Schidmt in 1999 [11]. It refers to the physiological phenomenon in response to a premature beat. After a ventricular premature contraction (VPC) and a compensatory pause, there is an increase in blood pressure because of the prolonged filling. Ref
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br Perioperative risk assessment of thromboembolism The curr
2019-06-26

Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical INCB3344 valve, chronic atrial fibrillation or venous thromboembolism who e
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GP ablation has been regarded
2019-06-26

GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc
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In an effort to determine
2019-06-26

In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi
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Validation study findings showed that knowledge KR had moder
2019-06-26

Validation study findings showed that knowledge (KR20=0.58) had moderate internal consistency. Even though this was fairly acceptable, the knowledge domain was considered a good test as KR20 tends to result in more conservative estimates than Cronbach’s alpha [28]. Enhancing the reliability of a que
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